Major Depressive Disorder (MDD)
Major Depressive Disorder, often simply called depression, is one of the most common and serious mental health conditions worldwide.
Major Depressive Disorder (MDD)
Major Depressive Disorder, often simply called depression, is one of the most common and serious mental health conditions worldwide. It goes far beyond temporary sadness, leading to persistent feelings of emptiness, hopelessness, and a loss of interest in previously enjoyable activities. MDD can significantly interfere with work, school, relationships, and daily functioning. In Saudi Arabia, depression has been reported as one of the most prevalent mental health issues, particularly among young adults and women, though stigma often prevents individuals from seeking help.
What constitutes MDD?
MDD is diagnosed when at least five depressive symptoms are present nearly every day for a minimum of two weeks, with at least one being depressed mood or loss of interest/pleasure. These symptoms must cause significant distress or impairment in functioning.
Symptoms and warning signs
- Persistent sadness, emptiness, or hopelessness
- Loss of interest in activities once enjoyed
- Changes in appetite (weight loss or gain)
- Sleep disturbances (insomnia or oversleeping)
- Fatigue or low energy
- Difficulty concentrating or making decisions
- Feelings of worthlessness, guilt, or self-blame
- Recurrent thoughts of death or suicide
Causes and risk factors
- Genetic predisposition (family history of depression)
- Imbalances in neurotransmitters such as serotonin and dopamine
- Stressful life events (loss, trauma, major change)
- Chronic illness or disability
- Substance abuse
- Cultural stigma, isolation, and lack of social support
Treatment approaches
- Medication: Antidepressants (SSRIs, SNRIs, atypical antidepressants) help balance brain chemistry
- Psychotherapy: CBT, interpersonal therapy, and psychodynamic therapy are effective
- Lifestyle interventions: regular exercise, healthy diet, structured sleep patterns, mindfulness
- Combined treatment: research shows best outcomes with both medication and therapy
- Advanced treatments (for resistant cases): electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS)
Why Act Center for Major Depressive Disorder (MDD) in Jeddah, Saudi Arabia?
Our experienced Major Depressive Disorder therapist in Jeddah, Saudi Arabia provide comprehensive treatment using therapy and medication to help patients overcome debilitating depression.
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